CD11c antibody [3.9],Genetex,GTX11029

Host

Mouse

Reactivity

Human, Mouse, Rat, Cynomolgus monkey, Rhesus Monkey

Application

WB ICC/IF IHC-P IHC-Fr FCM IP in vivo Neutralizing /Inhibition

Conjugate

Unconjugated

Platform ID

BAB562654378

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD11c antibody [3.9]
Cat. No.GTX11029
Gene ID (Entrez)3687
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Rat, Cynomolgus monkey, Rhesus Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Fr FCM IP in vivo Neutralizing /Inhibition
ClonalityMonoclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetITGAX
ImmunogenRheumatoid synovial fluid cells and fibronectin purified human monocytes
PurityProtein A/G purified
Appearance/FormLiquid
FormulationPBS, 150 mM NaCl,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Synonyms

CD11C,ITGAX,SLEB6,integrin subunit alpha X,CD11c,Integrin alpha X

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