CD134 antibody,Genetex,GTX12380

Host

Rabbit

Reactivity

Human

Application

WB

Conjugate

Unconjugated

Platform ID

BAB086892738

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameCD134 antibody
Cat. No.GTX12380
Gene ID (Entrez)7293
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration500 μg/ml (Please refer to the vial label for the specific concentration.)
TargetTNFRSF4
ImmunogenA synthetic peptide corresponding to a sequence at the N-terminus of human CD134(29-47aa LHCVGDTYPSNDRCCHECR).
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
Formulation0.1% Na₂HPO₄, 0.45% NaCl, 2.5% BSA,0.025% Thimerosal, 0.025% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]

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