CD141/Thrombomodulin Rabbit PolymAb®,ABclonal,A22989PM

Reactivity

Human

Application

WB, IHC-P, IF/ICC, FC, ELISA

Conjugate

Unconjugated

Platform ID

BAB243772342

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD141/Thrombomodulin Rabbit PolymAb®
Cat. No.A22989PM
Accession NumberP07204
Gene ID (Entrez)7056
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IHC-P, IF/ICC, FC, ELISA
Working DilutionsWB:1:2000 - 1:10000 | IHC-P:1:100 - 1:500 | IF/ICC:1:50 - 1:200 | FC:1:500 - 1:1000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight90kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.

Synonyms

TM; THRM; AHUS6; BDCA3; CD141; BDCA-3; THPH12

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