CD163 Rabbit mAb,ABclonal,A22619

Reactivity

Human

Application

WB, IF-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB226180790

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

Tel:
Fax:

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD163 Rabbit mAb
Cat. No.A22619
Accession NumberQ86VB7
Gene ID (Entrez)9332
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IF-P, ELISA
Working DilutionsWB:1:1000 - 1:2000 | IF-P:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC58325
Molecular Weight170kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Synonyms

M130; MM130; SCARI1; CD163

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.