CD163 antibody,Genetex,GTX35248

Host

Rabbit

Reactivity

Human, Mouse, Rat, Guinea pig

Application

WB IHC-P IHC-Fr

Conjugate

Unconjugated

Platform ID

BAB143965330

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD163 antibody
Cat. No.GTX35248
Gene ID (Entrez)9332
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Guinea pig
ConjugationUnconjugated
ApplicationWB IHC-P IHC-Fr
ClonalityPolyclonal
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCD163
ImmunogenKLH conjugated synthetic peptide derived from human CD163.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Synonyms

CD163 molecule , M130 , MM130 , SCARI1

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