CD163 antibody [EDHu-1],Genetex,GTX42365

Host

Mouse

Reactivity

Human, Mouse, Sheep, Bovine, Guinea pig, Pig, Rhesus Monkey

Application

WB ICC/IF IHC-P IHC-Fr FCM ELISA Immunoassay

Conjugate

Unconjugated

Platform ID

BAB403685662

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD163 antibody [EDHu-1]
Cat. No.GTX42365
Gene ID (Entrez)9332
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Sheep, Bovine, Guinea pig, Pig, Rhesus Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Fr FCM ELISA Immunoassay
ClonalityMonoclonal
Concentration1.0 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCD163
ImmunogenLeucocytes harvested from the pleural cavity of patients with idiopathic spontaneous pneumothorax
PurityProtein A purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Synonyms

CD163 molecule , M130 , MM130 , SCARI1

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