CD1b antibody [N2C3],Genetex,GTX112817
Host
Rabbit
Reactivity
Human
Application
WB
Conjugate
Unconjugated
Platform ID
BAB879558513

Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Specifications
Scientific Background
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq]
Synonyms
CD1b molecule , CD1 , CD1A , R1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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