CD21 Antibody (YA6156),MedChemexpress,HY-P86464

CD21 Antibody (YA6156) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD21.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,IHC-P,ICC/IF,IP,ELISA

Conjugate

Non-conjugated

Platform ID

BAB538425095

Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

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Contact

Tel: 609-228-6898
Fax: 609-228-5909

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD21 Antibody (YA6156)
Cat. No.HY-P86464
Accession NumberP20023
Gene ID (Entrez)1380
HostRabbit
IsotypeIgG
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,IP,ELISA
Working DilutionsIHC-P: 1:1000-1:4000; WB: 1:1000-1:5000; ICC/IF: 1:200-1:1000; ELISA: 1:5000-1:20000; IP: 1:50-1:200
ClonalityMonoclonal
Clone NumberYA6156
Molecular WeightPredicted band size: 113 kDa; Observed band size: 155 kDa
PurityProtein A
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

CD21 Protein, functioning as a receptor for complement C3d and HNRNPU, is integral to the activation of B lymphocytes. Through interactions with C3 and CD19, CD21 participates in immune responses and forms part of a complex that includes CD19, CR2/CD21, CD81, and IFITM1/CD225 in the membrane of mature B-cells. The intricate network of interactions, specifically via Sushi domains 1 and 2, emphasizes CD21's role in modulating immune signaling. Additionally, CD21 associates with FCER2, specifically through the C-terminus, highlighting its involvement in various cellular processes and underscoring its significance in B-cell activation and immune regulation.

Synonyms

CR2; C3DR; Complement receptor type 2; Cr2; Complement C3d receptor; Epstein-Barr virus receptor; EBV receptor; CD21

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