CD252 antibody [OX-89],Genetex,GTX27434

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq]

Tnf Superfamily Member 4 , Cd134L , Cd252 , Gp34 , Ox-40L , Ox4Ol , Tnlg2B , Txgp1 , Tnfsf4