CD27 antibody [O323] (APC-Cy7),Genetex,GTX01457-15

Host

Mouse

Reactivity

Human, Baboon, Cynomolgus monkey, Rhesus Monkey

Application

FCM

Conjugate

Allophycocyanin-Cyanine7 (APC-Cy7) Wavelength

Platform ID

BAB528470794

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD27 antibody [O323] (APC-Cy7)
Cat. No.GTX01457-15
Gene ID (Entrez)939
HostMouse
IsotypeIgG1
ReactivityHuman, Baboon, Cynomolgus monkey, Rhesus Monkey
ConjugationAllophycocyanin-Cyanine7 (APC-Cy7) Wavelength
ApplicationFCM
ClonalityMonoclonal
Concentration0.025 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCD27
PurityPurified by affinity chromatographyFrom tissue culture supernatant
Appearance/FormLiquid
Formulation10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Synonyms

CD27 molecule , CD27 , S152 , S152. LPFS2 , T14 , TNFRSF7 , Tp55

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