CD3 Polyclonal Antibody, PE Conjugated,Bioss,bs-10498R-PE

Host

Rabbit

Reactivity

Mouse

Application

WB

Conjugate

PE

Platform ID

BAB541550489

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD3 Polyclonal Antibody, PE Conjugated
Cat. No.bs-10498R-PE
Accession NumberQ7YRN2
Gene ID (Entrez)397455
HostRabbit
IsotypeIgG
ReactivityMouse
ConjugationPE
ApplicationWB
Working DilutionsWB:
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Synonyms

CD3; T-cell surface glycoprotein CD3 epsilon chain; CD3e

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