CD3 Rabbit mAb,ABclonal,A26443

Reactivity

Human

Application

WB, IF-P, IHC-P, FC, ELISA

Conjugate

Unconjugated

Platform ID

BAB219883814

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD3 Rabbit mAb
Cat. No.A26443
Accession NumberP07766
Gene ID (Entrez)916
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IF-P, IHC-P, FC, ELISA
Working DilutionsWB:1:500 - 1:1000 | IF-P:1:50 - 1:200 | IHC-P:1:50 - 1:200 | FC:1:100 - 1:500 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC68274
Molecular Weight23kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Synonyms

T3E; TCRE; IMD18; CD3epsilon

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