CD3 antibody [4D10A6],Genetex,GTX83391

Host

Mouse

Reactivity

Human

Application

FCM ELISA

Conjugate

Unconjugated

Platform ID

BAB943105467

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD3 antibody [4D10A6]
Cat. No.GTX83391
Gene ID (Entrez)919
HostMouse
IsotypeIgG2a
ReactivityHuman
ConjugationUnconjugated
ApplicationFCM ELISA
ClonalityMonoclonal
TargetCD247
ImmunogenPurified recombinant fragment of human CD3 expressed in E. Coli.
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.03% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

CD247 molecule , CD3-ZETA , CD3H , CD3Q , CD3Z , IMD25 , T3Z , TCRZ

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