CD3 antibody [CD3-12] (FITC),Genetex,GTX43629

Host

Rat

Reactivity

Human, Mouse, Rabbit, Bovine, Cat, Dog, Chicken, Pig, Alpaca, Amazon Parrot, Bullfrog, Cynomolgus monkey, Duck, Great horned owl (Bubo virginianus), Harbour Porpoise, Horse, Koala, Raccoon, Rhesus Monkey, Sea Lion, Spotted Hyena, Xenopus

Application

FCM

Conjugate

Fluorescein isothiocyanate (FITC) Wavelength

Platform ID

BAB030997052

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD3 antibody [CD3-12] (FITC)
Cat. No.GTX43629
HostRat
IsotypeIgG1
ReactivityHuman, Mouse, Rabbit, Bovine, Cat, Dog, Chicken, Pig, Alpaca, Amazon Parrot, Bullfrog, Cynomolgus monkey, Duck, Great horned owl (Bubo virginianus), Harbour Porpoise, Horse, Koala, Raccoon, Rhesus Monkey, Sea Lion, Spotted Hyena, Xenopus
ConjugationFluorescein isothiocyanate (FITC) Wavelength
ApplicationFCM
ClonalityMonoclonal
Concentration0.1 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenSynthetic peptide sequence derived from cytoplasmic epitope of CD3 (Glu-Arg-Pro-Pro-Pro-Val-Pro-Asn-Pro-Asp-Tyr-Glu-Pro-Cys) (ERPPPVPNPDYEPC )
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS, 1% BSA,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Synonyms

T3E Antibody , TCRE Antibody , CD3e molecule, epsilon (CD3-TCR complex) Antibody , CD3E Antibody

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