CD41 Antibody (YA535),MedChemexpress,HY-P80058
CD41 Antibody (YA535) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD41.
Host
Rabbit
Reactivity
Human
Application
WB,IHC-P
Conjugate
Non-conjugated
Platform ID
BAB066173034
Suppliers
(1)Biomedical Life sciences
MedChemexpress
Master of Bioactive Molecules
Contact
Tel: 609-228-6898
Fax: 609-228-5909
Email:
Specifications
Scientific Background
CD41, also known as integrin alpha-IIb/beta-3, serves as a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin, and vitronectin. It recognizes the R-G-D sequence in a broad range of ligands and specifically binds to the H-H-L-G-G-G-A-K-Q-A-G-D-V sequence in the fibrinogen gamma chain (By similarity). Upon activation, integrin alpha-IIb/beta-3 facilitates platelet-platelet interactions by binding soluble fibrinogen (PubMed:9111081), leading to rapid platelet aggregation that physically seals damaged endothelial surfaces (By similarity).
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Primary Antibodies>IHC Antibodies
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