CD41 antibody [MEM-06] (Biotin),Genetex,GTX78346

Host

Mouse

Reactivity

Human

Application

FCM

Conjugate

Biotin The reagent is free of unconjugated biotin.

Platform ID

BAB993092726

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD41 antibody [MEM-06] (Biotin)
Cat. No.GTX78346
Gene ID (Entrez)3674
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationBiotin The reagent is free of unconjugated biotin.
ApplicationFCM
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetITGA2B
ImmunogenLeukocytes of patient suffering from LGL-type leukaemia.
PurityPurified IgG
Appearance/FormLiquid
FormulationPBS,15mM Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]

Synonyms

BDPLT16 , BDPLT2 , CD41 , CD41B , GP2B , GPIIb , GT , GTA , HPA3 , ITGA2B , PPP1R93 , integrin subunit alpha 2b , Integrin alpha 2b

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