CD41 antibody [N2C1], Internal,Genetex,GTX113758

Host

Rabbit

Reactivity

Human, Mouse

Application

WB ICC/IF IHC-P IHC-Fr

Conjugate

Unconjugated

Platform ID

BAB194063800

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD41 antibody [N2C1], Internal
Cat. No.GTX113758
Gene ID (Entrez)3674
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Fr
ClonalityPolyclonal
Concentration0.25 mg/ml (Please refer to the vial label for the specific concentration.)
TargetITGA2B
ImmunogenRecombinant protein encompassing a sequence within the Extracellular domain of human CD41. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 1% BSA, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq]

Synonyms

integrin subunit alpha 2b , BDPLT16 , BDPLT2 , CD41 , CD41B , GP2B , GPIIb , GT , GTA , HPA3 , PPP1R93

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