CD44 antibody [IM7] (FITC),Genetex,GTX80087

Host

Rat

Reactivity

Human, Mouse, Cat, Dog, Pig, Baboon, Chimpanzee, Cynomolgus monkey, Horse, Rhesus Monkey

Application

FCM

Conjugate

Fluorescein isothiocyanate (FITC) Wavelength

Platform ID

BAB684884415

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD44 antibody [IM7] (FITC)
Cat. No.GTX80087
Gene ID (Entrez)960
HostRat
IsotypeIgG3b
ReactivityHuman, Mouse, Cat, Dog, Pig, Baboon, Chimpanzee, Cynomolgus monkey, Horse, Rhesus Monkey
ConjugationFluorescein isothiocyanate (FITC) Wavelength
ApplicationFCM
ClonalityMonoclonal
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCD44
ImmunogenDexamethasone-induced cells of the SJL mouse spontaneous myeloid leukemia M1
PurityPurified by affinity chromatographyFrom tissue culture supernatant
Appearance/FormLiquid
Formulation10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]

Synonyms

CD44 molecule (Indian blood group) , CDW44 , CSPG8 , ECMR-III , HCELL , HUTCH-I , IN , LHR , MC56 , MDU2 , MDU3 , MIC4 , Pgp1

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