CD45 Polyclonal Antibody, PE Conjugated,Bioss,bs-0522R-PE

Host

Rabbit

Reactivity

Human

Application

WB, FCM, IF(IHC-P), IF(ICC)

Conjugate

PE

Platform ID

BAB726095658

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD45 Polyclonal Antibody, PE Conjugated
Cat. No.bs-0522R-PE
Accession NumberP08575
Gene ID (Entrez)5788
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationPE
ApplicationWB, FCM, IF(IHC-P), IF(ICC)
Working DilutionsWB:1:300-5000 | FCM:1:20-100 | IF(IHC-P): | IF(ICC):
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).

Synonyms

LCA; LY5; B220; CD45; L-CA; T2; CD45R; GP18; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; PTPRC

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