CD59, Human, mAb MEM-43,Hycult Biotech,HM2120

Name: CD59, Human, mAb MEM-43,Hycult Biotech,HM2120
Brand: Buy Antibody
SKU: BAB133903955

The antibody is the prototypic antibody for the CD59 determinant, a PI-linked glycoprotein of 18-25 kDa, which is broadly expressed on most types of cells. The antigen is the major complement-protecting molecule of human cells. It is expressed on all leukocytes, erythrocytes and most other cell types. Binding of this antibody inhibits the complement-protecting activity of CD59. CD59 is one of the complement regulatory membrane proteins that is missing in Paroxysmal Nocturnal Haemoglobinuria (PNH). Anti CD59 reagents may be useful in the differential diagnosis of PNH type II and PNH type I. Recently a role for CD59 in LPS signal transduction has been reported in keratinocytes. The antibody reacts with well defined epitope (W40, R-53) on CD59 molecule.

Host

Human

Platform ID

BAB133903955

Frontstraat 2a 5405 PB Uden, The Netherlands

Tel: +31 (0)413 251335
Fax: +31(0)413 248353

Product Specifications

NameCD59, Human, mAb MEM-43

Cat. No.HM2120

HostHuman

IsotypeMouse IgG2a

FormulationSterile 0.2 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS and 0.1% bovine serum albumin with low endotoxin level.

StorageProduct should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Regulatory StatusResearch Use Only

Request a product

Please provide the required information below so that we can quickly source your products.