CD59 Polyclonal Antibody,Bioss,bs-1638R

Host

Rabbit

Reactivity

Human

Application

ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)

Conjugate

Unconjugated

Platform ID

BAB173159815

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD59 Polyclonal Antibody
Cat. No.bs-1638R
Accession NumberP13987
Gene ID (Entrez)966
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Working DilutionsELISA:1:500-1000 | FCM:1:20-100 | IHC-P:1:200-400 | IHC-F:1:100-500 | IF(IHC-P):1:50-200 | IF(IHC-F):1:50-200 | IF(ICC):1:50-200
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.

Synonyms

1F5; EJ16; EJ3; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF2; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-2; MAC-IP; p18-2; CD59 glycoprotein; 1F5 antigen; 2 kDa homologous restriction factor; MAC-inhibitory protein; MEM43 antigen; Membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; Protectin; CD59

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