CD62E/E-Selectin Rabbit mAb,ABclonal,A23836

Reactivity

Human

Application

WB, FC, ELISA

Conjugate

Unconjugated

Platform ID

BAB290661089

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

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Product Specifications
Scientific Background
Synonyms

Specifications

NameCD62E/E-Selectin Rabbit mAb
Cat. No.A23836
Accession NumberP16581
Gene ID (Entrez)6401
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, FC, ELISA
Working DilutionsWB:1:1000 - 1:4000 | FC:1:100 - 1:500 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC61987
Molecular Weight110-120kDa (Recombinant Protein)
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Synonyms

SELE; CD62E; ELAM; ELAM1; ESEL; LECAM2; E-selectin; CD62E/E-Selectin

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