CD62L antibody [DREG56] (Low Endotoxin),Genetex,GTX80176-00

Host

Mouse

Reactivity

Human

Application

WB IHC-Fr FCM IP Functional Assay

Conjugate

Unconjugated

Platform ID

BAB560221753

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD62L antibody [DREG56] (Low Endotoxin)
Cat. No.GTX80176-00
Gene ID (Entrez)6402
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-Fr FCM IP Functional Assay
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSELL
ImmunogenPMA-activated human peripheral blood leukocytes
PurityProtein A purified
Endotoxin LevelLow Endotoxin
Appearance/FormLiquid
FormulationFilter-sterilized PBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]

Synonyms

CD62L , LAM1 , LECAM1 , LEU8 , LNHR , LSEL , LYAM1 , PLNHR , SELL , TQ1 , selectin L , L-Selectin

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