CD68 (D4B9C) Rabbit Monoclonal Antibody (BSA and Azide Free)#26042,Cell Signaling Technology (CST),26042

CD68 (D4B9C) Rabbit Monoclonal Antibody (BSA and Azide Free) recognizes endogenous levels of total CD68 protein.

Host

Rabbit

Reactivity

Human, Monkey

Platform ID

BAB719511464

Cell Signaling Technology (CST)

Headquarters

3 Trask Lane Danvers, MA 01923

Cell Signaling Technology (CST)

Contact

Tel: 877-616-2355,978-867-2388
Fax: 877-616-2355

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD68 (D4B9C) Rabbit Monoclonal Antibody (BSA and Azide Free)#26042
Cat. No.26042
Accession NumberP34810
Gene ID (Entrez)34810
HostRabbit
SensitivityEndogenous
ReactivityHuman, Monkey
ImmunogenIgG
FormulationThis product is the carrier free version of product #76437. All data were generated using the same antibody clone in the standard formulation which contains BSA and glycerol.This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT&RUN, or CUT&Tag assays. If you require a carrier-free formulation for chromatin profiling, pleasecontact us. Optimal dilutions/concentrations should be determined by the end user.BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.
StorageStore at -20°C.This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles.A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.
Regulatory StatusResearch Use Only

Scientific Background

CD68 (macrosialin) is a heavily glycosylated transmembrane protein that is expressed by and commonly used as a marker for monocytes and macrophages (1,2). It is found on the plasma membrane, as well as endosomal and lysosomal membranes (1-3). It is proposed to bind OxLDL and has been observed as a homodimer (3,4).Rabinowitz, S.S. and Gordon, S. (1991)J Exp Med174, 827-36.Holness, C.L. and Simmons, D.L. (1993)Blood81, 1607-13.Ramprasad, M.P. et al. (1995)Proc Natl Acad Sci U S A92, 9580-4.Ramprasad, M.P. et al. (1996)Proc Natl Acad Sci U S A93, 14833-8.Alternate NamesCD68; CD68 antigen; CD68 molecule; DKFZp686M18236; Gp110; LAMP4; macrophage antigen CD68; Macrosialin; SCARD1; scavenger receptor class D, member 1

Synonyms

CD68; CD68 antigen; CD68 molecule; DKFZp686M18236; Gp110; LAMP4; macrophage antigen CD68; Macrosialin; SCARD1; scavenger receptor class D, member 1

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