CD68 (D4B9C) Rabbit Monoclonal Antibody (SignalFlexTMmFluorTMViolet 510 Conjugate)#78917,Cell Signaling Technology (CST),78917

CD68 (D4B9C) XP®Rabbit mAb (SignalFlexTM mFluorTM Violet 510 Conjugate) recognizes endogenous levels of total CD68 protein.

Host

Rabbit

Reactivity

Human, Monkey

Conjugate

SignalFlexTMmFluorTMViolet 510 Conjugate

Platform ID

BAB068511450

Cell Signaling Technology (CST)

Headquarters

3 Trask Lane Danvers, MA 01923

Cell Signaling Technology (CST)

Contact

Tel: 877-616-2355,978-867-2388
Fax: 877-616-2355

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD68 (D4B9C) Rabbit Monoclonal Antibody (SignalFlexTMmFluorTMViolet 510 Conjugate)#78917
Cat. No.78917
Accession NumberP34810
Gene ID (Entrez)34810
HostRabbit
SensitivityEndogenous
ReactivityHuman, Monkey
ConjugationSignalFlexTMmFluorTMViolet 510 Conjugate
ImmunogenIgG
FormulationSignalFlexTM conjugates are produced using highly validated Cell Signaling Technology®primary antibodies and conjugation methods that have been rigorously tested, ensuring high-quality conjugates and lot-to-lot consistency. These conjugates are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity. However, they are not tested on specific assays.Optimal dilutions/concentrations should be determined by the end user. When performing flow cytometry, we recommend using an isotype control conjugate at the same concentration as the antibody conjugate.
StorageSupplied in PBS (pH 7.2), less than 0.1% sodium azide, and 2 mg/mL BSA. Store at 4°C.Do not aliquot the antibody. Protect from light. Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD68 (macrosialin) is a heavily glycosylated transmembrane protein that is expressed by and commonly used as a marker for monocytes and macrophages (1,2). It is found on the plasma membrane, as well as endosomal and lysosomal membranes (1-3). It is proposed to bind OxLDL and has been observed as a homodimer (3,4).Rabinowitz, S.S. and Gordon, S. (1991)J Exp Med174, 827-36.Holness, C.L. and Simmons, D.L. (1993)Blood81, 1607-13.Ramprasad, M.P. et al. (1995)Proc Natl Acad Sci U S A92, 9580-4.Ramprasad, M.P. et al. (1996)Proc Natl Acad Sci U S A93, 14833-8.Alternate NamesCD68; CD68 antigen; CD68 molecule; DKFZp686M18236; Gp110; LAMP4; macrophage antigen CD68; Macrosialin; SCARD1; scavenger receptor class D, member 1

Synonyms

CD68; CD68 antigen; CD68 molecule; DKFZp686M18236; Gp110; LAMP4; macrophage antigen CD68; Macrosialin; SCARD1; scavenger receptor class D, member 1

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