CD68 (D4B9C) Rabbit Monoclonal Antibody (mFluorTMRed 780 Conjugate)#69165,Cell Signaling Technology (CST),69165

CD68 (D4B9C) Rabbit Monoclonal Antibody (mFluorTM Red 780 Conjugate) recognizes endogenous levels of total CD68 protein.

Host

Rabbit

Reactivity

Human, Monkey

Application

Flow Cytometry (Fixed/Permeabilized): 1:50

Platform ID

BAB818486462

Cell Signaling Technology (CST)

Headquarters

3 Trask Lane Danvers, MA 01923

Contact

Tel: 877-616-2355,978-867-2388
Fax: 877-616-2355

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD68 (D4B9C) Rabbit Monoclonal Antibody (mFluorTMRed 780 Conjugate)#69165
Cat. No.69165
Accession NumberP34810
Gene ID (Entrez)34810
HostRabbit
SensitivityEndogenous
ReactivityHuman, Monkey
ApplicationFlow Cytometry (Fixed/Permeabilized): 1:50
ImmunogenIgG
FormulationSupplied in PBS (pH 7.2), less than 0.1% sodium azide, and 2 mg/mL BSA. Store at 4°C.Do not aliquot the antibody. Protect from light. Do not freeze.
StorageSupplied in PBS (pH 7.2), less than 0.1% sodium azide, and 2 mg/mL BSA. Store at 4°C.Do not aliquot the antibody. Protect from light. Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD68 (macrosialin) is a heavily glycosylated transmembrane protein that is expressed by and commonly used as a marker for monocytes and macrophages (1,2). It is found on the plasma membrane, as well as endosomal and lysosomal membranes (1-3). It is proposed to bind OxLDL and has been observed as a homodimer (3,4).Rabinowitz, S.S. and Gordon, S. (1991)J Exp Med174, 827-36.Holness, C.L. and Simmons, D.L. (1993)Blood81, 1607-13.Ramprasad, M.P. et al. (1995)Proc Natl Acad Sci U S A92, 9580-4.Ramprasad, M.P. et al. (1996)Proc Natl Acad Sci U S A93, 14833-8.Alternate NamesCD68; CD68 antigen; CD68 molecule; DKFZp686M18236; Gp110; LAMP4; macrophage antigen CD68; Macrosialin; SCARD1; scavenger receptor class D, member 1

Synonyms

CD68; CD68 antigen; CD68 molecule; DKFZp686M18236; Gp110; LAMP4; macrophage antigen CD68; Macrosialin; SCARD1; scavenger receptor class D, member 1

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