CD68 (E3O7V) Mouse Chimeric Monoclonal Antibody#41077,Cell Signaling Technology (CST),41077

CD68 (E3O7V) Mouse Chimeric Monoclonal Antibody recognizes endogenous levels of total CD68 protein.

Host

Mouse

Reactivity

Mouse, Rat, Hamster

Application

Immunofluorescence (Frozen): 1:50 - 1:200

Platform ID

BAB657030205

Cell Signaling Technology (CST)

Headquarters

3 Trask Lane Danvers, MA 01923

Cell Signaling Technology (CST)

Contact

Tel: 877-616-2355,978-867-2388
Fax: 877-616-2355

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD68 (E3O7V) Mouse Chimeric Monoclonal Antibody#41077
Cat. No.41077
Accession NumberP31996
Gene ID (Entrez)31996, 12514
HostMouse
SensitivityEndogenous
ReactivityMouse, Rat, Hamster
ApplicationImmunofluorescence (Frozen): 1:50 - 1:200
Immunogenchimeric
FormulationSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C.Do not aliquot the antibody.
StorageSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C.Do not aliquot the antibody.
Regulatory StatusResearch Use Only

Scientific Background

CD68 (macrosialin) is a heavily glycosylated transmembrane protein that is expressed by and commonly used as a marker for monocytes and macrophages (1,2). It is found on the plasma membrane, as well as endosomal and lysosomal membranes (1-3). It is proposed to bind OxLDL and has been observed as a homodimer (3,4).Rabinowitz, S.S. and Gordon, S. (1991)J Exp Med174, 827-36.Holness, C.L. and Simmons, D.L. (1993)Blood81, 1607-13.Ramprasad, M.P. et al. (1995)Proc Natl Acad Sci U S A92, 9580-4.Ramprasad, M.P. et al. (1996)Proc Natl Acad Sci U S A93, 14833-8.Alternate NamesCd68; CD68 antigen; gp11; gp110; Lamp4; Macrosialin; Sca; Scard1

Synonyms

Cd68; CD68 antigen; gp11; gp110; Lamp4; Macrosialin; Sca; Scard1

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