CD74 Rabbit mAb,ABclonal,A24027

Reactivity

Human

Application

WB, IHC-P, IF/ICC, FC, ELISA

Conjugate

Unconjugated

Platform ID

BAB470208658

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD74 Rabbit mAb
Cat. No.A24027
Accession NumberP04233-2
Gene ID (Entrez)972
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IHC-P, IF/ICC, FC, ELISA
Working DilutionsWB:1:100000 - 1:400000 | IHC-P:1:10000 - 1:50000 | IF/ICC:1:200 - 1:800 | FC:1:500 - 1:1000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC56788
Molecular Weight35kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms

II; p33; CLIP; DHLAG; HLADG; Ia-GAMMA

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