CD74 antibody [Bu45],Genetex,GTX55453

Host

Mouse

Reactivity

Human

Application

ICC/IF IHC-Fr FCM IP Functional Assay

Conjugate

Unconjugated

Platform ID

BAB946814950

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD74 antibody [Bu45]
Cat. No.GTX55453
Gene ID (Entrez)972
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationICC/IF IHC-Fr FCM IP Functional Assay
ClonalityMonoclonal
Concentration1.0 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCD74
ImmunogenB lymphoblastoid cell line HFB1.
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Synonyms

CD74 molecule , DHLAG , HLADG , II , Ia-GAMMA , p33

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