CD74 antibody [LN2] (ready-to-use),Genetex,GTX73535

Host

Mouse

Reactivity

Human

Application

WB IHC-P IHC-Fr Functional Assay

Conjugate

Unconjugated

Platform ID

BAB798952165

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD74 antibody [LN2] (ready-to-use)
Cat. No.GTX73535
Gene ID (Entrez)972
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P IHC-Fr Functional Assay
ClonalityMonoclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetCD74
ImmunogenSU-DHL-4 lymphoma cells.
PurityPurified IgG
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Synonyms

CD74 molecule , DHLAG , HLADG , II , Ia-GAMMA , p33

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