CD8 alpha antibody [CD8/4391R],Genetex,GTX02616

Host

Rabbit

Reactivity

Human

Application

IHC-P Protein Array

Conjugate

Unconjugated

Platform ID

BAB531969114

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD8 alpha antibody [CD8/4391R]
Cat. No.GTX02616
Gene ID (Entrez)925
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P Protein Array
ClonalityMonoclonal
Concentration200 μg/ml (Please refer to the vial label for the specific concentration.)
TargetCD8A
ImmunogenSynthetic peptide corresponding to human CD8α residues within aa135-235
PurityProtein A/G purified
Appearance/FormLiquid
FormulationPBS, 0.05% BSA,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Synonyms

CD8a molecule , CD8 , Leu2 , p32

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