CD8 alpha antibody [OKT-8],Genetex,GTX14198

Host

Mouse

Reactivity

Human

Application

Depletion

Conjugate

Unconjugated

Platform ID

BAB226348296

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD8 alpha antibody [OKT-8]
Cat. No.GTX14198
Gene ID (Entrez)925
HostMouse
IsotypeIgG2a
ReactivityHuman
ConjugationUnconjugated
ApplicationDepletion
ClonalityMonoclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetCD8A
ImmunogenHuman CD8α
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationFilter-sterilized PBS, 0.01% Tween,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Synonyms

CD8,CD8A,CD8a molecule,Leu2,MAL,p32,CD8 alpha

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