CD8A Rabbit PolymAb®,ABclonal,A23305PM

Reactivity

Human, Mouse, Rat, Cynomolgus monkey

Application

WB, IF-F, IF-P, IHC-P, mIHC, ELISA

Conjugate

Unconjugated

Platform ID

BAB366735820

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCD8A Rabbit PolymAb®
Cat. No.A23305PM
Accession NumberP01732
Gene ID (Entrez)925
IsotypeIgG
ReactivityHuman, Mouse, Rat, Cynomolgus monkey
ConjugationUnconjugated
ApplicationWB, IF-F, IF-P, IHC-P, mIHC, ELISA
Working DilutionsWB:1:500 - 1:1000 | IF-F:1:200-1:400 | IF-P:1:50-1:200 | IHC-P:1:200 - 1:2000 | mIHC:1:200 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight40 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

CD8A;CD8;Leu2;MAL;p32

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