CDC25A antibody,Genetex,GTX20989

Host

Rabbit

Reactivity

Human

Application

WB IP

Conjugate

Unconjugated

Platform ID

BAB861455942

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCDC25A antibody
Cat. No.GTX20989
Gene ID (Entrez)993
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IP
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetCDC25A
ImmunogenSynthetic peptide representing a portion of the protein encoded by exon 7 (LocusLink ID 993).
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationTris-Citrate/Phosphate,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

CDC25A , CDC25A2 , cell division cycle 25A

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