CDC25B antibody [EPR3459(2)],Genetex,GTX63329

Host

Rabbit

Reactivity

Human

Application

WB IP

Conjugate

Unconjugated

Platform ID

BAB957909622

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCDC25B antibody [EPR3459(2)]
Cat. No.GTX63329
Gene ID (Entrez)994
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IP
ClonalityMonoclonal
TargetCDC25B
ImmunogenSynthetic peptide corresponding to residues in human Cdc25B
PurityTissue culture supernatant
Appearance/FormLiquid
FormulationBuffer, 0.05% BSA, 50% Glycerol,0.01% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]

Synonyms

cell division cycle 25B

Category Paths

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