CDC42EP2 antibody [N1C3],Genetex,GTX117891

Host

Rabbit

Reactivity

Mouse

Application

WB

Conjugate

Unconjugated

Platform ID

BAB828171926

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCDC42EP2 antibody [N1C3]
Cat. No.GTX117891
Gene ID (Entrez)10435
HostRabbit
IsotypeIgG
ReactivityMouse
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCDC42EP2
ImmunogenRecombinant protein encompassing a sequence within the center region of human CDC42EP2. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
Formulation0.1M Tris, 0.1M Glycine, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq]

Synonyms

CDC42 effector protein 2 , BORG1 , CEP2

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