CDKN1A/p21 Polyclonal Antibody, Cy7 Conjugated,Bioss,bs-0741R-Cy7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

IF(IHC-P), IF(IHC-F), IF(ICC)

Conjugate

Cy7

Platform ID

BAB789576437

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCDKN1A/p21 Polyclonal Antibody, Cy7 Conjugated
Cat. No.bs-0741R-Cy7
Accession NumberP38936
Gene ID (Entrez)12575
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationCy7
ApplicationIF(IHC-P), IF(IHC-F), IF(ICC)
Working DilutionsIF(IHC-P):1:50-200 | IF(IHC-F):1:50-200 | IF(ICC):1:50-200
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity).

Synonyms

P21; CDKI; CIP1; SDI1; Waf1; mda6; CAP2; Cdkn1; p21WAF; p21Cip1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein; Cdkn1a

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