CDKN1B (10B7) Monoclonal Antibody,Bioss,bsm-51281M

Host

Mouse

Reactivity

Human

Application

WB, IHC-P, IHC-F, IF

Conjugate

Unconjugated

Platform ID

BAB394487320

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCDKN1B (10B7) Monoclonal Antibody
Cat. No.bsm-51281M
Accession NumberP46527
Gene ID (Entrez)1027
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IF
Working DilutionsWB:1:300-5000 | IHC-P:1:200-400 | IHC-F: | IF:
ClonalityMonoclonal
Concentration0.5ug/ul
PurityPurified by Protein G.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Synonyms

KIP1; MEN4; CDKN4; MEN1B; P27KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; CDKN1B

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