CDKN1B/p27 KIP 1 Polyclonal Antibody,Bioss,bs-0742R
Host
Rabbit
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Conjugate
Unconjugated
Platform ID
BAB102082684

Bioss
Contact
Tel: +1.781.569.5821
Fax: +1.781.731.9286
Email:
Specifications
Scientific Background
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Synonyms
KIP1; MEN4; CDKN4; MEN1B; P27KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; CDKN1B
Category Paths
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