CDKN1B/p27 KIP 1 Polyclonal Antibody,Bioss,bs-0742R

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)

Conjugate

Unconjugated

Platform ID

BAB102082684

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameCDKN1B/p27 KIP 1 Polyclonal Antibody
Cat. No.bs-0742R
Accession NumberP46527
Gene ID (Entrez)1027
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Working DilutionsWB:1:300-5000 | ELISA:1:500-1000 | FCM:1:20-100 | IHC-P:1:200-400 | IHC-F:1:100-500 | IF(IHC-P):1:50-200 | IF(IHC-F):1:50-200 | IF(ICC):1:50-200
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Synonyms

KIP1; MEN4; CDKN4; MEN1B; P27KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; CDKN1B

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