CDX2 Antibody (YA3498),MedChemexpress,HY-P80983

CDX2 Antibody (YA3498) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDX2.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,IHC-P,ICC/IF,FC

Conjugate

Non-conjugated

Platform ID

BAB254516379

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

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Contact

Tel: 609-228-6898
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Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameCDX2 Antibody (YA3498)
Cat. No.HY-P80983
Accession NumberQ99626
Gene ID (Entrez)1045
HostRabbit
RRIDAB_3103012
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,FC
Working DilutionsWB: 1:500-1:1000; IHC-P: 1:50-1:100; ICC/IF: 1:50-1:200; FC: 1:50-1:100
ClonalityRecombinant,Monoclonal
Clone NumberYA3498
Molecular WeightPredicted band size: 34 kDa;Observed band size: 40 kDa
ImmunogenA synthesized peptide derived from human CDX2 aa11-76.
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

CDX2 is a transcription factor that regulates the transcription of multiple genes expressed in the intestinal epithelium (By similarity). It binds to the promoter of the intestinal sucrase-isomaltase SI and activates SI transcription (By similarity), as well as the DNA sequence 5'-ATAAAAACTTAT-3' in the promoter region of VDR to activate VDR transcription (By similarity). Additionally, CDX2 binds to and activates transcription of LPH (By similarity), and also activates transcription of CLDN2 and intestinal mucin MUC2 (By similarity). It further binds to the 5'-AATTTTTTACAACACCT-3' DNA sequence in the promoter region of CA1 and activates CA1 transcription (By similarity). CDX2 plays a crucial role in a broad range of functions, from early differentiation to the maintenance of the intestinal epithelial lining in both the small and large intestine, and preferentially binds to methylated DNA.

Synonyms

Caudal type homeo box 2 antibody; Caudal type homeo box transcription factor 2 antibody; Caudal type homeobox 2 antibody; Caudal type homeobox protein 2 antibody; Caudal type homeobox transcription factor 2 antibody; Caudal-type homeobox protein 2 antibody; CDX 2 antibody; CDX 3 antibody; CDX-3 antibody; Cdx2 antibody; CDX2_HUMAN antibody; CDX3 antibody; Homeobox protein CDX 2 antibody; Homeobox protein CDX-2 antibody;

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