CEA Antibody (YA917),MedChemexpress,HY-P81080

CEA Antibody (YA917) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CEA.

Host

Rabbit

Reactivity

Human

Application

WB,IHC-P,ICC/IF

Conjugate

Non-conjugated

Platform ID

BAB255116091

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

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Contact

Tel: 609-228-6898
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Email:

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Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameCEA Antibody (YA917)
Cat. No.HY-P81080
Accession NumberP06731
Gene ID (Entrez)1048
HostRabbit
RRIDAB_3103195
IsotypeIgG
SensitivityEndogenous
ReactivityHuman
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF
Working DilutionsWB: 1:500-1:1000; IHC-P: 1:50-1:100; ICC/IF: 1:50-1:200;
ClonalityMonoclonal,Recombinant
Clone NumberYA917
Molecular WeightPredicted band size: 77 kDa;Observed band size: 180-220 kDa
ImmunogenA synthesized peptide derived from human CEA(CD66e) aa1-702.
PurityAffinity Chromatography
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

CEA (Carcinoembryonic Antigen) is a cell surface glycoprotein involved in cell adhesion, intracellular signaling, and tumor progression. It mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. CEA functions as an oncogene by promoting tumor progression, including inducing resistance to anoikis in colorectal carcinoma cells. Additionally, CEA serves as a receptor for E. coli Dr adhesins, and binding of these adhesins leads to dissociation of the homodimer.

Synonyms

Carcinoembryonic antigen; Carcinoembryonic antigen related cell adhesion molecule 5; Carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CD66e antigen; CEACAM5; CEAM5_HUMAN; DKFZp781M2392; Meconium antigen 100.

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