CENPA antibody,Genetex,GTX134430

Host

Rabbit

Reactivity

Human

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB286030899

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCENPA antibody
Cat. No.GTX134430
Gene ID (Entrez)1058
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityPolyclonal
Concentration1.11 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCENPA
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CENPA. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015]

Synonyms

centromere protein A , CENP-A , CenH3

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