COMP antibody, Internal,Genetex,GTX81660

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB IHC-P FCM

Conjugate

Unconjugated

Platform ID

BAB125951452

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCOMP antibody, Internal
Cat. No.GTX81660
Gene ID (Entrez)1311
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB IHC-P FCM
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetCOMP
ImmunogenKLH conjugated synthetic peptide between 314-343 amino acids from the Central region of human COMP.
PurityProtein A purified, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2016]

Synonyms

cartilage oligomeric matrix protein , EDM1 , EPD1 , MED , PSACH , THBS5 , TSP5

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