CREB Antibody (YA491),MedChemexpress,HY-P80092

CREB Antibody (YA491) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CREB.

Host

Rabbit

Reactivity

Human,Mouse,Rat,Zebrafish

Application

WB,IHC-P,ICC/IF,FC,IF-Tissue

Conjugate

Non-conjugated

Platform ID

BAB378879185

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

MedChemexpress

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Email:

[email protected]

Product Specifications
Verification Image
Scientific Background

Specifications

NameCREB Antibody (YA491)
Cat. No.HY-P80092
Accession NumberP16220
Gene ID (Entrez)1385
HostRabbit
RRIDAB_3102299
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat,Zebrafish
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,FC,IF-Tissue
Working DilutionsWB: 1:500; ICC/IF: 1:500; IHC-P: 1:500-1:5000; FC: 1:1000; IF-Tissue: 1:200
ClonalityRecombinant,Monoclonal
Clone NumberYA491
Molecular WeightPredicted band size: 35 kDa；Observed band size: 42 kDa
ImmunogenSynthetic peptide corresponding to Human CREB.AA range:250-290.
PurityProtein A affinity purified.
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

Creb is a phosphorylation-dependent transcription factor that stimulates transcription by binding to the cAMP response element (CRE) in DNA, a sequence found in many viral and cellular promoters (By similarity). Its transcriptional activation is enhanced by TORC coactivators, which function independently of Ser-119 phosphorylation (PubMed:14536081). Creb is involved in various cellular processes, including the synchronization of circadian rhythms and the differentiation of adipose cells (By similarity). Additionally, it regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling (By similarity).

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