CRK Antibody (YA790),MedChemexpress,HY-P80630

CRK Antibody (YA790) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CRK.

Host

Mouse

Reactivity

Human

Application

WB

Conjugate

Non-conjugated

Platform ID

BAB812249918

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

MedChemexpress

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCRK Antibody (YA790)
Cat. No.HY-P80630
Accession NumberP46108
Gene ID (Entrez)1398
HostMouse
IsotypeIgG2b
SensitivityEndogenous
ReactivityHuman
ConjugationNon-conjugated
ApplicationWB
Working DilutionsWB: 1:500-1:1000
ClonalityMonoclonal
Clone NumberYA790
Molecular WeightPredicted band size: 34 kDa; Observed band size: 34 kDa
ImmunogenSynthetic peptide corresponding to Human CrkII.The exact sequence is proprietary to MCE.
Purityaffinity purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

CRK (3H7): This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]

Synonyms

Adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; CRK; CRKII; Proto-oncogene c-Crk

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.