CRY2 Rabbit pAb- ABclonal,ABclonal,A13289

Reactivity

Human, Rat

Application

WB, IF/ICC, ELISA

Conjugate

Unconjugated

Platform ID

BAB579767309

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameCRY2 Rabbit pAb- ABclonal
Cat. No.A13289
RRID#N/A
IsotypeIgG
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationWB, IF/ICC, ELISA
Working DilutionsWB:1:500 - 1:1000 | IF/ICC:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight70kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.

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