CTDSPL2 (D79G11) Rabbit Monoclonal Antibody#6932,Cell Signaling Technology (CST),6932

CTD small phosphatase-like protein 2 (CTDSPL2, HSPC129) is a putative RNA-polymerase II carboxy-terminal domain (CTD) phosphatase (1) that belongs to a small subfamily of CTD phosphatases (2). The CTD of RNA polymerase II contains multiple Y-S-P-T-S-P-S repeats that are phosphorylated during the transcription cycle (3,4). In general, CTD phosphatases regulate the reversible CTD phosphorylation state of RNA-polymerase II at several stages of RNA synthesis and during post-transcriptional modification (4-6). CTDSPL2 has several structural and functional similarities to other CTD phosphatases, including FCP1, SCP1, DULLARD, and UBLCP1 (1,2).Qian, H. et al. (2007)Mol Cell Biochem303, 183-8.Kim, Y. et al. (2007)Proc Natl Acad Sci USA104, 6596-601.Corden, J.L. et al. (1985)Proc Natl Acad Sci USA82, 7934-8.Ahn, S.H. et al. (2004)Mol Cell13, 67-76.Dahmus, M.E. (1996)J Biol Chem271, 19009-12.Goodrich, J.A. and Tjian, R. (1994)Cell77, 145-56.Alternate NamesCTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2; CTD small phosphatase like 2; CTD small phosphatase-like protein 2; CTDSP-like 2; CTDSPL2; CTSL2; FLJ10523; HSPC058; HSPC129; SCP4

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2; CTD small phosphatase like 2; CTD small phosphatase-like protein 2; CTDSP-like 2; CTDSPL2; CTSL2; FLJ10523; HSPC058; HSPC129; SCP4