CTLA4 antibody,Genetex,GTX13486
Host
Goat
Reactivity
Mouse
Application
WB ELISA
Conjugate
Unconjugated
Platform ID
BAB786580635
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
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Product Specifications
Scientific Background
Synonyms
Specifications
NameCTLA4 antibody
Cat. No.GTX13486
Gene ID (Entrez)12477
HostGoat
IsotypeIgG
ReactivityMouse
ConjugationUnconjugated
ApplicationWB ELISA
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetCtla4
Immunogenpurified recombinant mouse cytotoxic T-lymphocyte-associated molecule 4 extracellualr domain, expressed in mouse NSO cells.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 5% Trehalose,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only
Scientific Background
CTLA4 has a critical role in T cell differentiation and contributes to the maintenance of peripheral T cell tolerance to self antigens. It exerts its major effects on T cell immune responses via regulation of the cell cycle and may be involved in T-cell activation. It binds to B7-1 (CD80) and B7-2 (CD86), and it contains 1 immunoglobulin-like V-type domain. Widely expressed with highest levels in lymphoid tissues.
Synonyms
cytotoxic T-lymphocyte-associated protein 4 , Cd152 , Ctla-4 , Ly-56
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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