CUG-BP1 Recombinant Antibody,Bioss,bsm-62319r

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF

Conjugate

Unconjugated

Platform ID

BAB317601714

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCUG-BP1 Recombinant Antibody
Cat. No.bsm-62319r
Accession NumberQ92879
Gene ID (Entrez)10658
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF
Working DilutionsWB:1:300-5000 | IHC-P:FCM1:20-100 | IHC-F:IHC-P1:200-400 | IP:IHC-F1:100-500 | IF:ICC1:50-200 | Flow-Cyt:IP1-2ug | ICC/IF:IF
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts both as an activator and as a repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs. Activates SM exon 5 inclusion by antagonizing the repressive effect of PTB.

Synonyms

BRUNOL2; celf1; CUGBP; CUGBP1; EDEN BP; hNab50; NAB50; NAPOR.

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