CXCR4 antibody,Genetex,GTX21671

Host

Goat

Reactivity

Human, Rat

Application

WB IHC-P ELISA

Conjugate

Unconjugated

Platform ID

BAB737193088

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCXCR4 antibody
Cat. No.GTX21671
Gene ID (Entrez)7852
HostGoat
IsotypeIgG
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationWB IHC-P ELISA
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetCXCR4
ImmunogenSynthetic peptide TEEMGSGDYDSMKEPCFREENANFNKC corresponding to N-terminal extracellular domain of human CXCR4 receptor
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
Formulation10mM KHPO₄, 140mM NaCl, 0.1% BSA,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Synonyms

CD184,CXC motif chemokine receptor 4,CXCR4,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM,WHIMS,C-X-C motif chemokine receptor 4

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